Better care for iNPH patients

The Likvor CELDA™ System is the first commercial instrument for better diagnostics of idiopathic Normal Pressure Hydrocephalus (iNPH or NPH). Through automated and standardised protocols the Likvor CELDA System assess the cerebrospinal fluid system (CFS) dynamics, helping caregivers to make the correct diagnosis for suspected iNPH patients in shorter time.

Improved diagnostics

Through standardized and highly automated infusion tests the CELDA ™ Instrument assists in diagnosing and identifying candidates for shunt surgery. CELDA produces objective results, independent of patient and/or investigator performance.

Prevent unneccessary shunt surgery

The CELDA Instrument is the only commercial instrument that accurately can simulate the effect of having a shunt implant. Using the CELDA pulsativity curve test, patients that are diagnosed with iNPH but won’t benefit from a shunt implant can be identified without performing surgery.

Easy to use

The CELDA™ System contains integrated hardware and software and an easy to use interface for safe and efficient handling. The test protocols are automated and produces standardised reports making the work flow and analysis efficient.

A complete solution for assessing CSF dynamics

Pre-operative

Efficient CSF assessment in NPH diagnostics

Likvor CELDA™️ System sets a new standard for diagnostics of disease linked to disturbances in the cerebrospinal fluid system, such as normal pressure hydrocephalus (NPH). Using automated test protocols and standardised data the Likvor CELDA System enhances care givers ability to include or exclude NPH from the diagnosis. NPH are often mistaken for other neurological diseases such as Parkinson’s and Alzheimer’s, making a correct and objective assessments a high priority. 

Post-operative

Assess the functionality of CSF shunt devices

Following a shunt implant operation the Likvor CELDA™ System makes it easy to assess the CSF dynamics and observe the functionality of the shunt device. The CELDA Instrument lets you evaluate whether unchanged or worsened symptoms can be corrected by shunt adjustment and also to discover any cases of shunt dysfunction requiring surgical shunt revision. 

Background

Idiopathic Normal Pressure Hydrocephalus

Idiopathic normal pressure hydrocephalus, or iNPH, is an accumulation of cerebrospinal fluid, CSF, causing the ventricles of the brain to enlarge. Only 20% of iNPH patients are diagnosed and 15% get the correct treatment. When iNPH is suspected or if there is a need to exclude iNPH, this is the start of the usage of CELDA™️. Evidence before the CELDA™️ investigation include enlarged ventricles, and the triad of cardinal symptoms of NPH which include difficulty in balance and walking, dementia or cognitive impairment and urinary incontinence. Read more »

Guidelines

In 2005, guidelines for iNPH were published. In connection with this, a scheme was presented to show shunt-responsive normal pressure hydrocephalus pressure hydrocephalus on the basis of evidentiary tables.

The degree of certainty in the decision data based on the tests performed are in percent, far left. The red square marks what is included in an infusion test. The software for CELDA Instruments includes both tap tests, bolus tests if desired and CSF dynamics tests for a longer period of time, where all additions of tests contribute to improved prediction of whether a patient is helped by a shunt.

Easy implementation

Please consult with us to find the best way to implement the Likvor CELDA™ System in your operations. The instrument and tools are available for immediate delivery.

Purchase

For units that provide frequent CSF examinations purchasing the CELDA System is a preferred option.

Lease

Eliminate the initial purchase cost and pay only per investigation, with a contracted annual minimum.

As a Service

A complete service option where Likvor provide equipment and a trained operator that perform the examinations.

Contact

Please reach out to us to discuss the possibilities for implementing CELDA System in your investigations or research.